Angers, Stephane • Functional Architecture of Signal Transduction Protein Complexes

Associate Professor
Associate Dean, Research
Canada Research Chair in Functional Architecture of Signal Transduction Complexes

Full Faculty CPO Member 

Functional Architecture of Signal Transduction Protein Complexes

We are principally interested in the study of signal transduction initiated by the Wnt and Hedgehog families of growth factors:

Wnt and Hedgehog are secreted glycoproteins with essential roles during development but also in the adult for the control of cell proliferation, determination of cell fate and cell survival. Their importance is best revealed in the case of several human cancers where mutations are found within proteins of their corresponding signalling pathways.

Read more at: http://pharmacy.utoronto.ca/users/angers-s

Area(s) of interest in Pharmaceutical Oncology:

  • Cancer biology
  • Cancer genomics/genetics
  • Animal models
  • Cancer target discovery
  • Synthesis of anti-cancer agents
  • Antibody Engineering 3
  • Polymer chemistry
  • Nanomedicines
  • Pharmacokinetics
  • Imaging
  • Radiation medicine
  • Surgical oncology
  • Formulation science
  • Toxicology
  • Clinical trials
  • Experimental therapeutics
  • Immunotherapy
  • Cancer stem cells
  • Phototherapy
  • Patient care
  • Health economics
  • Public policy
  • Continuing Education
  • Other

 Trainees within CPO:

  • Smith, Joe
  • Zed, Fred